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1.

Itaconate as a key regulator of respiratory disease.

Michalaki, Christina; Albers, Gesa J; Byrne, Adam J.

Clin Exp Immunol; 215(2): 120-125, 2024 02 07.

Artículo en Inglés | MEDLINE | ID: mdl-38018224

2.

Pulmonary Epithelial Cell-Derived Cytokine TGF-ß1 Is a Critical Cofactor for Enhanced Innate Lymphoid Cell Function.

Denney, Laura; Byrne, Adam J; Shea, Thomas J; Buckley, James S; Pease, James E; Herledan, Gaelle M F; Walker, Simone A; Gregory, Lisa G; Lloyd, Clare M.

Immunity; 43(5): 945-58, 2015 Nov 17.

Artículo en Inglés | MEDLINE | ID: mdl-26588780

3.

CYFRA 21-1 Predicts Progression in Idiopathic Pulmonary Fibrosis: A Prospective Longitudinal Analysis of the PROFILE Cohort.

Molyneaux, Philip L; Fahy, William A; Byrne, Adam J; Braybrooke, Rebecca; Saunders, Peter; Toshner, Richard; Albers, Gesa; Chua, Felix; Renzoni, Elisabetta A; Wells, Athol U; Karkera, Yakshitha; Oballa, Eunice; Saini, Gauri; Nicholson, Andrew G; Jenkins, R Gisli; Maher, Toby M.

Am J Respir Crit Care Med; 205(12): 1440-1448, 2022 06 15.

Artículo en Inglés | MEDLINE | ID: mdl-35363592

4.

DNA Methylome Alterations Are Associated with Airway Macrophage Differentiation and Phenotype during Lung Fibrosis.

McErlean, Peter; Bell, Christopher G; Hewitt, Richard J; Busharat, Zabreen; Ogger, Patricia P; Ghai, Poonam; Albers, Gesa J; Calamita, Emily; Kingston, Shaun; Molyneaux, Philip L; Beck, Stephan; Lloyd, Clare M; Maher, Toby M; Byrne, Adam J.

Am J Respir Crit Care Med; 204(8): 954-966, 2021 10 15.

Artículo en Inglés | MEDLINE | ID: mdl-34280322

5.

The Respiratory Microbiome in Chronic Hypersensitivity Pneumonitis Is Distinct from That of Idiopathic Pulmonary Fibrosis.

Invernizzi, Rachele; Wu, Benjamin G; Barnett, Joseph; Ghai, Poonam; Kingston, Shaun; Hewitt, Richard J; Feary, Johanna; Li, Yonghua; Chua, Felix; Wu, Zhe; Wells, Athol U; George, Peter M; Renzoni, Elisabetta A; Nicholson, Andrew G; Rice, Alexandra; Devaraj, Anand; Segal, Leopoldo N; Byrne, Adam J; Maher, Toby M; Lloyd, Clare M; Molyneaux, Philip L.

Am J Respir Crit Care Med; 203(3): 339-347, 2021 02 01.

Artículo en Inglés | MEDLINE | ID: mdl-32692582

6.

Lung fibrosis enters the iron age.

Ogger, Patricia P; Byrne, Adam J.

J Pathol; 252(1): 1-3, 2020 09.

Artículo en Inglés | MEDLINE | ID: mdl-32510612

7.

Bacterial burden in the lower airways predicts disease progression in idiopathic pulmonary fibrosis and is independent of radiological disease extent.

Invernizzi, Rachele; Barnett, Joseph; Rawal, Bhavin; Nair, Arjun; Ghai, Poonam; Kingston, Shaun; Chua, Felix; Wu, Zhe; Wells, Athol U; Renzoni, Elizabeth R; Nicholson, Andrew G; Rice, Alexandra; Lloyd, Clare M; Byrne, Adam J; Maher, Toby M; Devaraj, Anand; Molyneaux, Philip L.

Eur Respir J; 55(4)2020 04.

Artículo en Inglés | MEDLINE | ID: mdl-31980496

8.

The Transferrin Receptor CD71 Delineates Functionally Distinct Airway Macrophage Subsets during Idiopathic Pulmonary Fibrosis.

Allden, Sarah J; Ogger, Patricia P; Ghai, Poonam; McErlean, Peter; Hewitt, Richard; Toshner, Richard; Walker, Simone A; Saunders, Peter; Kingston, Shaun; Molyneaux, Philip L; Maher, Toby M; Lloyd, Clare M; Byrne, Adam J.

Am J Respir Crit Care Med; 200(2): 209-219, 2019 07 15.

Artículo en Inglés | MEDLINE | ID: mdl-31051082

9.

An Alarmin Role for P2Y₁₃ Receptor during Viral-driven Asthma Exacerbations.

Byrne, Adam J; Saglani, Sejal; Snelgrove, Robert J.

Am J Respir Crit Care Med; 205(3): 263-265, 2022 02 01.

Artículo en Inglés | MEDLINE | ID: mdl-34936856

10.

IRF5 controls both acute and chronic inflammation.

Weiss, Miriam; Byrne, Adam J; Blazek, Katrina; Saliba, David G; Pease, James E; Perocheau, Dany; Feldmann, Marc; Udalova, Irina A.

Proc Natl Acad Sci U S A; 112(35): 11001-6, 2015 Sep 01.

Artículo en Inglés | MEDLINE | ID: mdl-26283380

11.

Pulmonary macrophages: key players in the innate defence of the airways.

Byrne, Adam J; Mathie, Sara A; Gregory, Lisa G; Lloyd, Clare M.

Thorax; 70(12): 1189-96, 2015 Dec.

Artículo en Inglés | MEDLINE | ID: mdl-26286722

12.

Perinatal paracetamol exposure in mice does not affect the development of allergic airways disease in early life.

Lee, Debbie C P; Walker, Simone A; Byrne, Adam J; Gregory, Lisa G; Buckley, James; Bush, Andrew; Shaheen, Seif O; Saglani, Sejal; Lloyd, Clare M.

Thorax; 70(6): 528-36, 2015 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-25841236

13.

Histamine-driven responses are sustained via a bioactive metabolite.

Velez, Tania E; Byrne, Adam J; Wechsler, Joshua B; Krier-Burris, Rebecca A; Hulse, Kathryn E; Bryce, Paul J.

J Allergy Clin Immunol; 143(6): 2287-2290.e1, 2019 06.

Artículo en Inglés | MEDLINE | ID: mdl-30738840

14.

Cutting edge: histamine is required for IL-4-driven eosinophilic allergic responses.

Swartzendruber, Julie A; Byrne, Adam J; Bryce, Paul J.

J Immunol; 188(2): 536-40, 2012 Jan 15.

Artículo en Inglés | MEDLINE | ID: mdl-22156496

15.

Antigen-fixed leukocytes tolerize Th2 responses in mouse models of allergy.

Smarr, Charles B; Hsu, Chia-Lin; Byrne, Adam J; Miller, Stephen D; Bryce, Paul J.

J Immunol; 187(10): 5090-8, 2011 Nov 15.

Artículo en Inglés | MEDLINE | ID: mdl-21976774

16.

IRF5 is a specific marker of inflammatory macrophages in vivo.

Weiss, Miriam; Blazek, Katrina; Byrne, Adam J; Perocheau, Dany P; Udalova, Irina A.

Mediators Inflamm; 2013: 245804, 2013.

Artículo en Inglés | MEDLINE | ID: mdl-24453413

17.

Type 1 invariant natural killer T cells in chronic inflammation and tissue fibrosis.

Kumar, Vipin; Hertz, Marc; Agro, Albert; Byrne, Adam J.

Front Immunol; 14: 1260503, 2023.

Artículo en Inglés | MEDLINE | ID: mdl-37818376

18.

Airway soluble CSF1R predicts progression in patients with idiopathic pulmonary fibrosis.

Oldham, Justin M; Johnson, Kirk W; Albers, Gesa J; Calamita, Emily; Mah, Jordina; Ghai, Poonam; Hewitt, Richard J; Maher, Toby M; Molyneaux, Philip L; Huang, Michael; Byrne, Adam J.

ERJ Open Res; 9(4)2023 Jul.

Artículo en Inglés | MEDLINE | ID: mdl-37465557

19.

Lung extracellular matrix modulates KRT5⁺ basal cell activity in pulmonary fibrosis.

Hewitt, Richard J; Puttur, Franz; Gaboriau, David C A; Fercoq, Frédéric; Fresquet, Maryline; Traves, William J; Yates, Laura L; Walker, Simone A; Molyneaux, Philip L; Kemp, Samuel V; Nicholson, Andrew G; Rice, Alexandra; Roberts, Edward; Lennon, Rachel; Carlin, Leo M; Byrne, Adam J; Maher, Toby M; Lloyd, Clare M.

Nat Commun; 14(1): 6039, 2023 09 27.

Artículo en Inglés | MEDLINE | ID: mdl-37758700

20.

Obesity dysregulates the pulmonary antiviral immune response.

Almond, Mark; Farne, Hugo A; Jackson, Millie M; Jha, Akhilesh; Katsoulis, Orestis; Pitts, Oliver; Tunstall, Tanushree; Regis, Eteri; Dunning, Jake; Byrne, Adam J; Mallia, Patrick; Kon, Onn Min; Saunders, Ken A; Simpson, Karen D; Snelgrove, Robert J; Openshaw, Peter J M; Edwards, Michael R; Barclay, Wendy S; Heaney, Liam M; Johnston, Sebastian L; Singanayagam, Aran.

Nat Commun; 14(1): 6607, 2023 10 19.

Artículo en Inglés | MEDLINE | ID: mdl-37857661

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